In the gene therapy strategy for mice with sickle cell disease, how is c-Myc removed from the HbS/HbS iPS cells?

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HbS/HbS iPS cells are treated with dsRNA to knock down expression of c-Myc in the cells.

HbS/HbS iPS cells are treated with tyrosine kinase, which acts as an inhibitor of c-Myc expression.

HbS/HbS iPS cells were infected with an adenovirus expressing CRE recombinase to remove c-Myc.

HbS/HbS iPS cells were infected with an adenovirus expressing Oct4 and Sox2, transcription factors that block transcription of c-Myc.

 

asked Jun 5, 2013 in Genetics by GeneX ~Top Expert~ (7,947 points)
    

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HbS/HbS iPS cells were infected with an adenovirus expressing CRE recombinase to remove c-Myc.

 

answered Jun 5, 2013 by GeneX ~Top Expert~ (7,947 points)

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