Virus-based gene therapy is being studied for the treatment of diseases such as cystic fibrosis and sickle cell disease. Because most viral vectors integrate into the host genome, there is concern about where the DNA integrates and if it could become mutagenic (as seen in the SCID trials). Which viral vector could you choose if you want to avoid integration into the genome?

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Lentivirus

  

Adenovirus

  

Retrovirus

  

Adeno-associated virus

 

asked Jun 5, 2013 in Genetics by GeneX ~Top Expert~ (7,941 points)
    

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Adenovirus

answered Jun 5, 2013 by GeneX ~Top Expert~ (7,941 points)

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