How are BACs different from plasmids?

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BACs have a different origin of replication than plasmids, which allows fewer copies of the BAC per cell.

BACs can be expressed in yeast and bacteria, whereas plasmids can only be expressed in bacteria.

BACs contain cos sequences that allow DNA to be integrated into the host genome, whereas plasmids remain separate from the bacterial host genome and require selectable markers to be maintained in the host.

BACs have a single cloning site, whereas plasmids have a multiple cloning site (MCS).

 

asked Jun 5, 2013 in Genetics by GeneX ~Top Expert~ (7,947 points)
    

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BACs have a different origin of replication than plasmids, which allows fewer copies of the BAC per cell.

 

answered Jun 5, 2013 by GeneX ~Top Expert~ (7,947 points)

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