Discovered by Alexander Fleming in 1929, penicillin has been an effective antibiotic against a broad spectrum of infectious bacteria. Why has there been a dramatic increase in penicillin-resistant strains of bacteria in recent years?

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Penicillin-resistance genes are transferred from resistant strains to nonresistant strains, leading to the evolution of penicillin resistance due to long generation times and underuse of penicillin in recent years.

Penicillin is a natural derivative of the fungus Penicillium. Bacteria respond more quickly to other antibiotics because they are designed to kill specific types of bacteria and are not broad-spectrum like penicillin.

Through the use of newer antibiotics such as ampicillin or amoxicillin, penicillin is prescribed more rarely. Through disuse of penicillin, bacteria developed resistance to that particular antibiotic.

Resistance is caused by evolution by natural selection through overuse of penicillin, as well as the rapid transfer of penicillin-resistance genes within and among bacterial species.

 

asked May 13, 2013 in Genetics by GeneX ~Top Expert~ (7,947 points)
    

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Resistance is caused by evolution by natural selection through overuse of penicillin, as well as the rapid transfer of penicillin-resistance genes within and among bacterial species.
answered May 13, 2013 by GeneX ~Top Expert~ (7,947 points)

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