Hereditary hemochromatosis (HH) is a genetic condition that causes "iron overload." Patients with severe forms of the disease must donate blood regularly to remove excess iron from their bloodstreams. Clinically, it is difficult to determine which HH patients will actually develop increased iron levels and the adverse symptoms associated with the disorder. Which type of inheritance pattern describes the inability to predict whether an individual with the HH allele will develop the disorder based on their genotype?

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Incomplete penetrance

  

Pleiotropy

  

Epistasis

  

Variable expressivity

 

asked May 5, 2013 in Genetics by GeneX ~Top Expert~ (7,941 points)
    

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Incomplete penetrance

answered May 5, 2013 by GeneX ~Top Expert~ (7,941 points)

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