Ras is a protein that is activated by the growth factor EGF. Active Ras binds to GTP, whereas inactive Ras is bound to GDP. A mutation in codon 12 of Ras is found in many human cancers because it results in a form of Ras that remains tightly bound to GTP, allowing cells to divide rapidly and uncontrollably. Which type of mutation likely results in this constitutively active Ras?

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Amorphic

  

Neomorphic

  

Hypermorphic

  

Hypomorphic

 

asked May 5, 2013 in Genetics by GeneX ~Top Expert~ (7,941 points)
    

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Hypermorphic
answered May 5, 2013 by GeneX ~Top Expert~ (7,941 points)

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