Defects in the Short Stature Homeobox (SHOX) genes result in a wide range of phenotypic disorders. Some individuals have severe skeletal defects, called Leri-Weill dyschondrosteosis (LWD), and others have a milder defect, known as SHOX-related short stature. If both copies of an allele must be present for a normal phenotype and a defect in one copy of the allele is sufficient to cause a mutant phenotype, the allele is said to be _______. Reference:

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asked May 5, 2013 in Genetics by GeneX ~Top Expert~ (7,933 points)

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answered May 5, 2013 by GeneX ~Top Expert~ (7,933 points)

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