p53 is a tumor suppressor gene that inhibits CDK2. What effect would you expect to see in cells that lack functional p53?

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They will become "stuck" in the G0 phase, so they would not be able to grow or divide.

  

They would be unable to activate cell cycle checkpoints at G2, so cells would divide very rapidly.

  

They would be unable to synthesize DNA, so the chromosomes could not be replicated.

  

They would be prevented from beginning mitosis, so cells would divide very slowly.

 

asked May 2, 2013 in Genetics by anonymous
    

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They would be unable to activate cell cycle checkpoints at G2, so cells would divide very rapidly.

answered May 2, 2013 by anonymous

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