What is the probability the following parents will have a child that is susceptible heart disease?

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SNPs are inherited in a Mendelian fashion and are often polygenic in nature. We can think of SNPs in terms of either contributing or non-contributing alleles. A study of SNPs correlated with heart disease has shown that heart problems are severe if 8 or more of the alleles at 5 loci are of the contributing variety. What is the probability the following parents will have a child that is susceptible heart disease?

 
a.  AaBbccDDEE x AaBbCCDdEe
 
b.  AaBbCcDdEe x AABbCCDdEE
asked Apr 11, 2013 in Genetics by anonymous
    

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