SNPs are inherited in a Mendelian fashion and are often polygenic in nature. We can think of SNPs in terms of either contributing or non-contributing alleles. A study of SNPs correlated with heart disease has shown that heart problems are severe if 8 or more of the alleles at 5 loci are of the contributing variety. What is the probability the following parents will have a child that is susceptible heart disease?
a. AaBbccDDEE x AaBbCCDdEe
b. AaBbCcDdEe x AABbCCDdEE