In mature B cells, different variable (V) and joining (J) segments of DNA combine and are then connected to constant (C) regions before transcription. Why is this observation so important for understanding acquired immunity?

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Recombination of V and J DNA regions helps to explain the diversity of immunoglobulin molecules that are part of acquired immunity.

Recombination is an important step in initiating the inflammatory response.

It was important to show that the V and C genes get closer together on the chromosome where they are located.

Recombination is required for production of a wide array of antigens in the body.

 

asked Jan 1, 2013 in Biology by anonymous
    

1 Answer

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Recombination of V and J DNA regions helps to explain the diversity of immunoglobulin molecules that are part of acquired immunity.

 

answered Jan 1, 2013 by anonymous

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