Which of the following must occur for shotgun sequencing to work effectively?

+2 votes

 

Each BAC is sequenced and overlapping sections are aligned to create a draft of the genome sequence.

Many copies of "shotgun clones" are cut into 1-kb fragments that are sequenced, and overlapping sections are aligned to create a draft of the genome sequence.

The genomic DNA is directly sequenced and overlapping sections are aligned to create a draft of the genome sequence.

Many copies of each BAC are cut into 1-kb fragments that are sequenced, and overlapping sections are aligned to create a draft of the genome sequence.

 

asked Dec 27, 2012 in Biology by anonymous
    

1 Answer

+1 vote

 

Many copies of each BAC are cut into 1-kb fragments that are sequenced, and overlapping sections are aligned to create a draft of the genome sequence.

 

answered Dec 27, 2012 by Luffy ~Expert~ (977 points)

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