Sickle-cell disease is a recessive genetic disorder in which hemoglobin is improperly folded, leading to the breakdown of red blood cells. Which would be the first step in finding the gene involved in this disorder?

+1 vote

 

Create a cDNA library from any cell in a human with sickle-cell disease.

Sequence the hemoglobin gene of an individual with sickle-cell disease.

Isolate mRNA from bone marrow and spleen cells, where red blood cells are synthesized, from an individual with sickle-cell disease.

Isolate mRNA from white blood cells from the circulatory system of an individual with sickle-cell disease.

 

asked Dec 27, 2012 in Biology by anonymous
    

1 Answer

+1 vote

 

Isolate mRNA from bone marrow and spleen cells, where red blood cells are synthesized, from an individual with sickle-cell disease.

 

answered Dec 27, 2012 by JPx ~Expert~ (379 points)

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