Which of the following experiments best supports the idea that a transcriptional regulatory sequence can be located in an intron of a gene?

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The intron of a gene is deleted, the gene is introduced into mouse cells, and the mRNA levels are measured. These mRNA levels are compared to a normal gene that is also introduced into mouse cells. The mutated gene shows no mRNA transcription whereas the normal one does.

The intron of a gene is deleted, the gene is introduced into mouse cells, and the mRNA levels are measured showing no mRNA expression.

The gene containing all introns intact is introduced into mouse cells and the mRNA levels are measured. The mRNA is transcribed at high levels.

The exon of a gene is deleted, the gene is introduced into mouse cells, and the mRNA levels are measured. These mRNA levels are compared to a normal gene that is also introduced into mouse cells. The mutated gene shows no mRNA transcription whereas the normal one does.

 
asked Dec 27, 2012 in Biology by anonymous
    

1 Answer

0 votes

 

The intron of a gene is deleted, the gene is introduced into mouse cells, and the mRNA levels are measured. These mRNA levels are compared to a normal gene that is also introduced into mouse cells. The mutated gene shows no mRNA transcription whereas the normal one does.

 

answered Dec 27, 2012 by anonymous

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