You have isolated an E. coli mutant that is abnormal for trp operon regulation. The mutation is located close to the structural genes for enzymes involved in tryptophan biosynthesis but it is not in any of the structural genes. Initiation of transcription of the trp operon occurs constitutively in this mutant, regardless of whether tryptophan is present in the medium. Which if the following is the best hypothesis for the effect of this mutation?

+2 votes



asked Nov 23, 2012 in Genetics by GeneX ~Top Expert~ (7,947 points)

1 Answer

+1 vote

Loss of function mutation in the trp operator.

answered Nov 23, 2012 by GeneX ~Top Expert~ (7,947 points)

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