What would happen if a mutation in the trp repressor gene prevented the repressor from binding to tryptophan?

+2 votes

The lacIS mutation is trans-dominant to wild type lacI+ (a partial diploid  lacIS / lacI+ has the same phenotype as lacIS  ).  The lacIS mutation prevents the lac repressor from binding to it's allosteric regulator, allolactose.  Let's define a similar mutation in the trpR gene "trpRnocanbindtryptophan " and then create a partial diploid that contained two copies of the trpRgene:  trpRtrpRnocanbindtryptophan .  If the partial diploid was wild type for all other trp operon DNA, what would it's phenotype be?



asked Nov 23, 2012 in Genetics by GeneX ~Top Expert~ (7,947 points)

1 Answer

+1 vote

Initiation of trp operon transcription would be repressible, just like wild type.

answered Nov 23, 2012 by GeneX ~Top Expert~ (7,947 points)

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