Two genes in the same region of a chromosome are expressed in reciprocal patterns: Gene 1 is expressed in cell types A, B and C but not in cell types D, E and F, whereas gene 2 is expressed in cell types D, E and F but not in cell types A, B or C. A mutant is isolated that expresses both gene in all 6 cell types. The mutation is found to be recessive. Which of the following is the best explanation of the nature of the mutation?

+2 votes

 

 

asked Nov 23, 2012 in Genetics by GeneX ~Top Expert~ (7,947 points)
    

1 Answer

+1 vote

The mutation is a loss of function mutation in a gene that encodes a trans-acting regulator that binds to an insulator sequence.

answered Nov 23, 2012 by GeneX ~Top Expert~ (7,947 points)

Related questions




...