Polydactyly is a human autosomal dominant condition that produces extra fingers and toes. Studies of hundreds of families with polydactyly have determined that penetrance for the dominant allele is 70%. Hospital-based surveys of live births find that 1 in 40,000 infants has a new case of polydactyly. Use this information to estimate the mutation rate of the gene.

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asked Nov 22, 2012 in Genetics by GeneX ~Top Expert~ (7,933 points)

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1 in 56,000 births

answered Nov 22, 2012 by GeneX ~Top Expert~ (7,933 points)

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