Is the mutation in ade1 considered to be a forward mutation or a reversion?

+1 vote

Two different mutations are identified in a haploid strain of yeast. The first prevents the synthesis of adenine by a nonsense mutation of the ade-1 gene. In this mutation, a base-pair substitution changes a tryptophan codon ({\rm UGG}) to a stop codon ({\rm UGA}). The second affects one of several duplicate {\rm tRNA}genes. This base-pair substitution mutation changes the anticodon sequence of a {\rm tRNA}_{{\rm Trp}}from 3'-{\rm ACC} - 5' to 3'-{\rm ACU} - 5'.

 

Part A

Is the mutation in ade1 considered to be a forward mutation or a reversion?

 

Part B

Is the mutation in the tRNAtrp considered to be a forward mutation or a reversion?

 

 

Part C

Assuming there are no other mutations in the genome, will this double-mutant yeast strain be able to grow on minimal medium?

asked Nov 22, 2012 in Genetics by GeneX ~Top Expert~ (7,947 points)
    

1 Answer

+1 vote

Part A

forward mutation

 

Part B

forward mutation

 

Part C

yes

answered Nov 22, 2012 by GeneX ~Top Expert~ (7,947 points)

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