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A man and a woman are each heterozygous carriers of an autosomal recessive mutation of a disorder that is fatal in infancy. They both want to have multiple children, but they are concerned about the risk of the disorder appearing in one or more of their children.

+3 votes

 

Part A
Determine the probability of the couple having five children with no children being affected by the disorder.
 
Part B
Determine the probability of the couple having five children with one child being affected by the disorder.

 

 

Part C
Determine the probability of the couple having five children with two children being affected by the disorder.
 
Part D
Determine the probability of the couple having five children with three children being affected by the disorder.
 
Part E
Determine the probability of the couple having five children with four children being affected by the disorder.
 
Part F
Determine the probability of the couple having five children with all children being affected by the disorder.
asked Nov 21, 2012 in Genetics by GeneX ~Top Expert~ (7,773 points)
    

1 Answer

+1 vote

Part A:

0.237

 

Part B:

0.396

 

Part C:

0.264

 

Part D:

0.088

 

Part E:

0.015

 

Part F:

0.001

answered Nov 21, 2012 by GeneX ~Top Expert~ (7,773 points)

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