What is the function of lipoprotein lipase?

+1 vote

 

What is the function of lipoprotein lipase?
 

 

asked Oct 16, 2012 in Science by mebu229 (46 points)
    

1 Answer

+2 votes

LPL encodes lipoprotein lipase, which is expressed on endothelial cells in the heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Through catalysis, VLDL is converted to IDL and then to LDL. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism

 

Refer to: http://en.wikipedia.org/wiki/Lipoprotein_lipase#Function

answered Oct 16, 2012 by kirby ~Expert~ (3,020 points)

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